KMID : 0355420030270030459
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Journal of Korean Academy of Oral Health 2003 Volume.27 No. 3 p.459 ~ p.470
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Effect of Potassium Alum and Sugar Substitutes on the Growth of Streptococcus mutans
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Abstract
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Traditionally, Koreans have used potassium alum by mouth rinse when they suffered from stomatitis. This study was carried out to investigate the combined effect of potassium alum with aspartame, sorbitol and xylitol on the growth of Streptococcus mutans (S, mutans). The relative growth ratio of S. mutans JC-2 cultured at different concentrations of potassium alum and different concentrations of aspartame, sorbitol and xylitol was examined. The combined effect of different concentrations of potassium alum with 0.5 and 10.0% of aspartame, sorbitol and xylitol was examined. The lowest minimum inhibitory concentration of potassium alum was 5.0 mg/ml against S. mutans JC-2. The relative growth ratio of potassium alum on S. mutans JC-2 was affected at the concentration of 2.0 mg/ml. The growth of S. mutans JC-2 decreased at the concentration of 10.0% of aspartame and sorbitol. Also, a combination of potassium alum and sugar substitutes was more effective against S. mutans than the use of one sugar substitute alone. The inhibitory effect of potassium alum and sugar substitutes on S mutans may be an important mechanism of caries prevention by potassium alum.
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